Limonin
Request a quote| Catalog Number | ACM1180718 |
| Product Name | Limonin |
| CAS Number | 1180-71-8 |
| Structure |  |
| Description | Limonin is a triterpenoid enriched in citrus fruits, which has antivirus and antitumor ability.IC50 Value:Target: HIV; anticancerLimonin is a triterpenoid aglycone that is a bitter principle of citrus fruits. Limonin is chemically induced carcinogenesis inhibitor and HIV-1 replication inhibitor. Limonin has anti-proliferative, proapoptotic activity on several cancer cell lines and inhibits azoxymethane-induced colon cancer in rats. Limonin also inhibits HIV-1 replication in culturedf monocytes, macrophages, and mononuclear cells, perhaps by inhibition of HIV-1 protease activity. |
| IUPAC Name | (1R,2R,7S,10R,13R,14R,16S,19S,20S)-19-(Furan-3-yl)-9,9,13,20-tetramethyl-4,8,15,18-tetraoxahexacyclo[11.9.0.02,7.02,10.014,16.014,20]docosane-5,12,17-trione |
| Synonyms | Evodia lactone |
| Molecular Weight | 470.51 |
| Molecular Formula | C26H30O8 |
| Canonical SMILES | CC1(C2CC(=O)C3(C(C24COC(=O)CC4O1)CCC5(C36C(O6)C(=O)OC5C7=COC=C7)C)C)C |
| Inchi | InChI=1S/C26H30O8/c1-22(2)15-9-16(27)24(4)14(25(15)12-31-18(28)10-17(25)33-22)5-7-23(3)19(13-6-8-30-11-13)32-21(29)20-26(23,24)34-20/h6,8,11,14-15,17,19-20H,5,7,9-10,12H2,1-4H3/t14-,15-,17-,19-,20+,23-,24-,25+,26+/m0/s1 |
| InChIKey | KBDSLGBFQAGHBE-MSGMIQHVSA-N |
| Boiling Point | 67 °C |
| Melting Point | 298 °C |
| Flash Point | 358 °C |
| Purity | 98%+ |
| Density | 1.39±0.1 g/cm³ |
| Appearance | Powder |
| Storage | 2-8 °C |
| Refractive Index | 1.602 |
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