D-Mannose
Request a quoteCatalog Number | ACM3458284 |
CAS | 3458-28-4 |
Structure | ![]() |
Synonyms | (+)-Mannose,Carubinose,D(+)-Mannose,Mannose,Seminose |
Molecular Weight | 180.16 |
Molecular Formula | C6H12O6 |
Boiling Point | 232.96 °C |
Melting Point | 133-140 °C (lit.) |
Purity | 98% |
Density | 1.539 g/cm³ |
Solubility | Soluble in water |
Appearance | White powder |
Application | D-Mannose, a white crystalline powder, serves a vital role in glycosylation processes within human metabolism and cellular functions. This carbohydrate, structurally akin to glucose, is responsible for the N and O glycosylation of proteins, including those used in infant formulas and the T helper cell-derived cytokine interleukin-17A, which is crucial for cell signaling. Found naturally in fruits such as cranberries and peaches, D-mannose is particularly effective in preventing urinary tract infections (UTIs) by binding to the lectins on E. coli bacteria's fimbria, thereby facilitating their expulsion via urination. Additionally, D-mannose is used in treating carbohydrate-deficient glycoprotein syndrome and serves as a reference standard in monosaccharide analysis. Its slow absorption in the gastrointestinal tract and substantial excretion in the urine make it the most effective supplement for UTI prevention and treatment. Furthermore, D-mannose is utilized in selecting transfected sorghum seeds and as a culture medium supplement for human cell lines, underscoring its multifaceted applications in both health and research contexts. |
Physical State | Powder |
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