D-Mannose

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Catalog Number ACM3458284
CAS 3458-28-4
Structure {[CurrentData.Name]}
Synonyms (+)-Mannose,Carubinose,D(+)-Mannose,Mannose,Seminose
Molecular Weight 180.16
Molecular Formula C6H12O6
Boiling Point 232.96 °C
Melting Point 133-140 °C (lit.)
Purity 98%
Density 1.539 g/cm³
Solubility Soluble in water
Appearance White powder
Application D-Mannose, a white crystalline powder, serves a vital role in glycosylation processes within human metabolism and cellular functions. This carbohydrate, structurally akin to glucose, is responsible for the N and O glycosylation of proteins, including those used in infant formulas and the T helper cell-derived cytokine interleukin-17A, which is crucial for cell signaling. Found naturally in fruits such as cranberries and peaches, D-mannose is particularly effective in preventing urinary tract infections (UTIs) by binding to the lectins on E. coli bacteria's fimbria, thereby facilitating their expulsion via urination. Additionally, D-mannose is used in treating carbohydrate-deficient glycoprotein syndrome and serves as a reference standard in monosaccharide analysis. Its slow absorption in the gastrointestinal tract and substantial excretion in the urine make it the most effective supplement for UTI prevention and treatment. Furthermore, D-mannose is utilized in selecting transfected sorghum seeds and as a culture medium supplement for human cell lines, underscoring its multifaceted applications in both health and research contexts.
Physical State Powder

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