Wedelolactone

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Catalog Number ACM524129
CAS 524-12-9
Structure {[CurrentData.Name]}
Description Wedelolactone suppresses LPS-induced caspase-11 expression by directly inhibits the IKK Complex. Wedelolactone also inhibits 5-lipoxygenase (5-Lox) with an IC50 of 2.5 μM. Wedelolactone induces caspase-dependent apoptosis in prostate cancer cells via downregulation of PKCε without inhibiting Akt. Wedelolactone can extract from Eclipta alba, and it can be used for the research of cancer.
Synonyms Pentafluorobenzaldehyde
Molecular Weight 314.25
Molecular Formula C16H10O7
Canonical SMILES COC1=CC(=C2C(=C1)OC(=O)C3=C2OC4=CC(=C(C=C43)O)O)O
Purity 99.91%

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