Shikonin
Request a quote| Catalog Number | ACM517895 |
| CAS | 517-89-5 |
| Structure | ![{[CurrentData.Name]}](https://resource.alfa-chemistry.com/structure/517-89-5.gif) |
| Description | Shikonin is a major component of a Chinese herbal medicine named zicao. Shikonin is a potent TMEM16A chloride channel inhibitor with an IC50 of 6.5 μM. Shikonin is a specific pyruvate kinase M2 (PKM2) inhibitor and can also inhibit TNF-α and NF-κB pathway. Shikonin decreases exosome secretion through the inhibition of glycolysis. Shikonin inhibits AIM2 inflammasome activation. |
| Synonyms | C.I. 75535 |
| Molecular Weight | 288.30 |
| Molecular Formula | C16H16O5 |
| Purity | 98% |
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