Neriifolin

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Catalog Number ACM466079
CAS 466-07-9
Structure {[CurrentData.Name]}
Description Neriifolin, a CNS-penetrating cardiac glycoside, is an inhibitor of the Na+, K+-ATPase. Neriifolin can target beclin 1, inhibits the formation of LC3-associated phagosomes and ameliorates experimental autoimmune encephalomyelitis (EAE) development. Neriifolin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells[2.
Molecular Weight 534.68
Molecular Formula C30H46O8
Canonical SMILES O[C@@]12[C@@]3([H])[C@@](CC[C@@]1([C@](C4=CC(OC4)=O)([H])CC2)C)([H])[C@@]5([C@](C[C@H](CC5)O[C@H]6[C@H]([C@@H]([C@H]([C@@H](O6)C)O)OC)O)([H])CC3)C
Purity 99%
Appearance Solid
Storage Powder-20°C, 3 years; In solvent-80°C. 6 months; -20°C, 1 month.

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