Mollugin
Request a quote| Catalog Number | ACM55481884 |
| CAS | 55481-88-4 |
| Structure | ![{[CurrentData.Name]}](https://resource.alfa-chemistry.com/structure/55481-88-4.gif) |
| Description | Mollugin is an orally active and potent NF-κB inhibitor. Mollugin induces S-phase arrest of HepG2 cells, and increased intracellular reactive oxygen species (ROS) levels. Mollugin induces DNA damage in HepG2 cells, as well as an increase in the expression of p-H2AX. Mollugin shows anti-cancer effect by inhibiting TNF-α-induced NF-κB activation. Mollugin enhances the osteogenic action of BMP-2 (bone morphogenetic protein 2) via the p38-Smad signaling pathway. |
| IUPAC Name | methyl 6-hydroxy-2,2-dimethylbenzo[h]chromene-5-carboxylate |
| Molecular Weight | 284.3 |
| Molecular Formula | C17H16O4 |
| Canonical SMILES | CC1(C=CC2=C(O1)C3=CC=CC=C3C(=C2C(=O)OC)O)C |
| Inchi | InChI=1S/C17H16O4/c1-17(2)9-8-12-13(16(19)20-3)14(18)10-6-4-5-7-11(10)15(12)21-17/h4-9,18H,1-3H3 |
| InChIKey | VLGATXOTCNBWIT-UHFFFAOYSA-N |
| Purity | 98% |
| Appearance | Yellow powder |
| Storage | 4°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light). |
Ask Your Question
