Name: Β-Cyclodextrin
SKU: ACM7585399
Rating: 5 (1 reviews)

Catalog Number	ACM7585399
CAS	7585-39-9
Structure
Description	DryPowder, Liquid; Liquid;Virtually odourless white or almost white crystalline solid
IUPAC Name	(1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31S,33R,35R,36R,37R,38R,39R,40R,41R,42R,43R,44R,45R,46R,47R,48R,49R)-5,10,15,20,25,30,35-heptakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34-tetradecaoxaoctacyclo[31.2.2.23,6.28,11.213,16.218,21.223,26.228,31]nonatetracontane-36,37,38,39,40,41,42,43,44,45,46,47,48,49-tetradecol
Molecular Weight	1134.98
Molecular Formula	C42H70O35
Canonical SMILES	C(C1C2C(C(C(O1)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)OC5C(OC(C(C5O)O)OC6C(OC(C(C6O)O)OC7C(OC(C(C7O)O)OC8C(OC(O2)C(C8O)O)CO)CO)CO)CO)CO)CO)O)O)O
Inchi	InChI=1S/C42H70O35/c43-1-8-29-15(50)22(57)36(64-8)72-30-9(2-44)66-38(24(59)17(30)52)74-32-11(4-46)68-40(26(61)19(32)54)76-34-13(6-48)70-42(28(63)21(34)56)77-35-14(7-49)69-41(27(62)20(35)55)75-33-12(5-47)67-39(25(60)18(33)53)73-31-10(3-45)65-37(71-29)23(58)16(31)51/h8-63H,1-7H2/t8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-/m1/s1
InChIKey	WHGYBXFWUBPSRW-FOUAGVGXSA-N
Purity	98%
Solubility	Sparingly soluble in water; freely soluble in hot water; slightly soluble in ethanol
Appearance	Solid
Application	Β-Cyclodextrin serves as a versatile cyclodextrin commonly used across pharmaceutical, food, and chemical industries due to its ability to form inclusion complexes. This cyclic oligosaccharide is produced naturally from starch through enzymatic conversion and features seven alpha-(1->4) linked D-glucopyranose units. Its unique molecular structure, characterized by a hydrophobic internal cavity and a hydrophilic external surface, allows it to effectively encapsulate various guest molecules. In pharmaceuticals, β-cyclodextrin is primarily employed to enhance the solubility and bioavailability of poorly soluble drugs, mitigate gastrointestinal irritation, and prevent undesirable interactions between drugs and excipients. While being affordable and widely available, it is noteworthy that β-cyclodextrin exhibits nephrotoxicity and should not be used in parenteral formulations. Additionally, it is utilized to mask unpleasant tastes and stabilize formulations in oral tablet and capsule preparations. Beyond pharmaceuticals, β-cyclodextrin finds applications in drug delivery, agriculture, environmental engineering, and the formulation of cosmetics and eye drops, where it enhances drug solubility and stability, reducing irritation and facilitating better absorption.
Storage	Powder-20°C, 3 years; 4°C, 2 years; In solvent-80°C, 6 months; -20°C, 1 month.