Α-Cyclodextrin

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Catalog Number ACM10016203-2
CAS 10016-20-3
Structure {[CurrentData.Name]}
Description Hexagonal plates or blade-shaped needles. (NTP, 1992);DryPowder
IUPAC Name (1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31R,32R,33R,34R,35R,36R,37R,38R,39R,40R,41R,42R)-5,10,15,20,25,30-hexakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29-dodecaoxaheptacyclo[26.2.2.23,6.28,11.213,16.218,21.223,26]dotetracontane-31,32,33,34,35,36,37,38,39,40,41,42-dodecol
Molecular Weight 972.84
Molecular Formula C36H60O30
Canonical SMILES C(C1C2C(C(C(O1)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)OC5C(OC(C(C5O)O)OC6C(OC(C(C6O)O)OC7C(OC(O2)C(C7O)O)CO)CO)CO)CO)CO)O)O)O
Inchi InChI=1S/C36H60O30/c37-1-7-25-13(43)19(49)31(55-7)62-26-8(2-38)57-33(21(51)15(26)45)64-28-10(4-40)59-35(23(53)17(28)47)66-30-12(6-42)60-36(24(54)18(30)48)65-29-11(5-41)58-34(22(52)16(29)46)63-27-9(3-39)56-32(61-25)20(50)14(27)44/h7-54H,1-6H2/t7-,8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-/m1/s1
InChIKey HFHDHCJBZVLPGP-RWMJIURBSA-N
Melting Point 532 °F (decomposes) (NTP, 1992)
Purity 98%
Application Α-Cyclodextrin is a versatile compound serving multiple purposes across various fields, including food, medical, and pharmaceutical applications. It acts primarily as a crucial ingredient for dietary and health benefits, offering capabilities such as lowering blood low-density lipoprotein cholesterol and blood triglyceride levels. In the food and beverage industry, Α-Cyclodextrin serves as a fiber ingredient with effective emulsification properties, making it valuable in fat-free or fat-containing desserts and as a substitute for egg white in confectionery and bakery items. In pharmaceuticals, its unique structural properties allow Α-Cyclodextrin to form inclusion complexes with small molecules, enhancing the solubility, stability, and bioavailability of active drug compounds, while also masking unpleasant tastes and converting liquids into solid forms. It plays a role in controlled drug release and increases insulin and leptin sensitivity. Additionally, its ability to form stable complexes with dietary fat reduces the absorption of fat in the body, making it a valuable component in health-focused formulations. The hydrophobic cavity and hydrophilic exterior make it adept at forming complexes with a range of guest molecules, thus expanding its utility in products aimed at improving bioavailability and stability.

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