Azelaic Acid

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Catalog Number ACM123999-2
CAS 123-99-9
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Description Azelaic acid is a synthetic dicarboxylic acid that is commonly used in the treatment of acne and rosacea. It is also sometimes prescribed for other skin conditions, such as hyperpigmentation and melasma.
Azelaic acid works by inhibiting the growth of acne-causing bacteria on the skin, reducing inflammation, and helping to unclog pores. It is also a mild exfoliant, which helps to remove dead skin cells and improve skin texture.
IUPAC Name Nonanedioic acid
Synonyms Anchoec acid
Molecular Weight 188.22
Molecular Formula C9H16O4
Canonical SMILES C(CCCC(=O)O)CCCC(=O)O
Inchi InChI=1S/C9H16O4/c10-8(11)6-4-2-1-3-5-7-9(12)13/h1-7H2,(H,10,11)(H,12,13)
InChIKey BDJRBEYXGGNYIS-UHFFFAOYSA-N
Boiling Point 286 °C/100 mmHg(lit.)
Melting Point 98 °C
Flash Point 215 °C
Purity 98%
Density 1.029 g/cm³
Solubility Soluble in hot water, alcohol, organic solvents
Appearance Solid
Application 1. Treatment of Acne: Azelaic Acid is commonly used as a topical treatment for mild to moderate acne. It works by reducing the growth of bacteria that causes acne, and it also helps to unclog pores and reduce inflammation.
2. Treatment of Rosacea: Azelaic Acid also has anti-inflammatory properties that make it an effective treatment for rosacea, a chronic skin condition that causes facial redness, swelling, and tiny bumps. It helps to reduce inflammation and redness in the affected areas.
3. Hyperpigmentation: Azelaic Acid is effective to treat hyperpigmentation, a condition where patches of skin become darker than the surrounding skin. It inhibits the enzyme responsible for the production of melanin, the pigment that gives color to the skin.
4. Skin Lightening: Azelaic Acid is also used in skin lightening products as it effectively reduces the production of melanin that makes skin color darker.
5. Hair Loss: Azelaic Acid has been shown to be effective in treating pattern baldness or androgenetic alopecia. It works by inhibiting the production of DHT, a hormone that is responsible for hair loss.
6. Anti-aging: Azelaic Acid stimulates collagen production, which helps to reduce fine lines and wrinkles, making it a useful ingredient in anti-aging products.
Storage Store below +30 °C
Physical State Solid
Refractive Index 1.4303

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